Exosomes Promote Colorectal Carcinoma Progression
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Colorectal carcinoma (CRC) is a prevalent and deadly form of cancer, posing a significant threat to global health. The discovery of exosomes isolated from CRC cells has shed light on the complex mechanisms underlying the progression of this malignancy. These tiny vesicles have been found to play a pivotal role in promoting CRC advancement by modulating key regulatory genes, enhancing cancer cell proliferation, inhibiting apoptosis, and manipulating various signaling pathways. Moreover, extensive research has established a direct correlation between exosomes derived from CRC cells and the induction of epithelial-mesenchymal transition (EMT) and angiogenesis, two critical processes implicated in cancer progression.